Twin Cities campus

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Twin Cities Campus

Experimental and Clinical Pharmacology M.S.

Experimental and Clinical Pharmacology
College of Pharmacy
Link to a list of faculty for this program.
Contact Information
Department of Experimental and Clinical Pharmacology, University of Minnesota College of Pharmacy, 7-115 Weaver-Densford Hall, 308 Harvard Street S.E., Minneapolis, MN 55455 (612-625-2160)
Email: grad-ecp@umn.edu
Website: https://z.umn.edu/ecpgrad
  • Program Type: Master's
  • Requirements for this program are current for Fall 2024
  • Length of program in credits: 34
  • This program does not require summer semesters for timely completion.
  • Degree: Master of Science
Along with the program-specific requirements listed below, please read the General Information section of this website for requirements that apply to all major fields.
The Experimental and Clinical Pharmacology (ECP) graduate program was designed specifically for students interested in clinical research. Its goal is to advance the science of human pharmacology and therapeutics to improve the safe, effective, and economical use of drugs by patients. Students study such topics as experimental pharmacotherapy, drug metabolism, infectious disease, neuroscience/neuropharmacology, pharmacometrics, and pharmacogenomics. Graduates are prepared for distinguished careers in clinical research.
Program Delivery
  • via classroom (the majority of instruction is face-to-face)
Prerequisites for Admission
The preferred undergraduate GPA for admittance to the program is 3.00.
A U.S. bachelor's degree or a comparable foreign degree from a recognized college or university is required.
Preference is given to candidates who have had professionally-related pharmacy education, but those from other fields such as biology, chemistry, statistics, and public health will be considered.
Other requirements to be completed before admission:
All international students who are non-English speakers are required to submit TOEFL scores. TOEFL test date must be within 2 years of program start. However, applicants who have completed 24 quarter credits or 16 semester credits within the past 24 months in residence as full-time students at recognized institutions of higher learning in the United States or other English-speaking countries before entering the University of Minnesota are generally exempted from this requirement. GRE required by all students except for applicants that have completed a PharmD at a U.S.-accredited institution.
Special Application Requirements:
Students are generally admitted to the ECP program for fall semester only. All application materials should be submitted by the admissions deadline listed on the departmental website. Applications received after the application deadline will be considered on a space-available basis only. Application to the ECP program at the University of Minnesota is done entirely online.
International applicants must submit score(s) from one of the following tests:
  • TOEFL
    • Internet Based - Total Score: 79
    • Internet Based - Writing Score: 21
    • Internet Based - Reading Score: 19
The preferred English language test is Test of English as Foreign Language.
Key to test abbreviations (TOEFL).
For an online application or for more information about graduate education admissions, see the General Information section of this website.
Program Requirements
Plan A: Plan A requires 24 major credits, up to credits outside the major, and 10 thesis credits. The final exam is oral.
Plan B: Plan B requires 34 major credits and up to credits outside the major. The final exam is oral.
This program may be completed with a minor.
Use of 4xxx courses toward program requirements is permitted under certain conditions with adviser approval.
A minimum GPA of 3.00 is required for students to remain in good standing.
At least 2 semesters must be completed before filing a Degree Program Form.
Required Courses (7 credits)
Take the following courses.
ECP 5220 - Regulatory Issues in Drug Research (2.0 cr)
ECP 8230 - Principles of Clinical Pharmacology (2.0 cr)
ECP 8983 - Scientific Communications in Experimental and Clinical Pharmacology (1.0 cr)
ECP 8982 - Inter-Institutional Journal Club in Translational Research (1.0 cr)
ECP 8100 - Seminar (1.0 cr)
Statistical Analysis (4 credits)
Select at least one of the following courses in consultation with the advisor. Two courses are preferred. A second course will count towards Electives.
PUBH 6450 - Biostatistics I (4.0 cr)
PUBH 6451 - Biostatistics II (4.0 cr)
STAT 5101 - Theory of Statistics I (4.0 cr)
STAT 5102 - Theory of Statistics II (4.0 cr)
Electives (13 credits)
Select electives, in consultation with the director of graduate studies and/or the advisor, to complete the master's minimum credit requirement.
ANAT 5xxx
ANAT 6xxx
ANAT 7xxx
ANSC 5xxx
ANSC 8xxx
BBE 5xxx
BBE 8xxx
BICB 5xxx
BICB 8xxx
BINF 5xxx
BIOC 5xxx
BIOC 6xxx
BIOL 5xxx
BIOL 6xxx
BIOL 8xxx
BMEN 5xxx
BMEN 8xxx
BMSC 8xxx
BTHX 5xxx
BTHX 8xxx
CGSC 8xxx
CHEM 5xxx
CHEM 8xxx
CLS 5xxx
CLS 8xxx
CMB 5xxx
CMB 8xxx
ECHO 4xxx
ECP 5xxx
ECP 8xxx
EEB 5xxx
EEB 8xxx
GCD 5xxx
GCD 6xxx
GCD 8xxx
HINF 5xxx
HINF 8xxx
MATH 5xxx
MATH 8xxx
MCDG 8xxx
MEDC 5xxx
MEDC 8xxx
MICA 8xxx
NSC 5xxx
NSC 8xxx
NSCI 5xxx
NSCI 6xxx
NURS 5xxx
NURS 6xxx
NURS 7xxx
NURS 8xxx
PHAR 5xxx
PHAR 6xxx
PHAR 7xxx
PHCL 5xxx
PHCL 8xxx
PHM 5xxx
PHM 6xxx
PHM 8xxx
PHSL 5xxx
PHSL 6xxx
PHSL 8xxx
PUBH 5xxx
PUBH 6xxx
PUBH 7xxx
PUBH 8xxx
SAPH 5xxx
SAPH 8xxx
SCB 5xxx
SCB 8xxx
SCIC 8xxx
STAT 5xxx
STAT 8xxx
TXCL 5xxx
TXCL 8xxx
VMED 5xxx
VMED 8xxx
BIOC 8xxx
Select Plan A or Plan B
Plan A
Take exactly 10 credit(s) from the following:
· ECP 8777 - Thesis Credits: Master's (1.0-18.0 cr)
-OR-
Plan B
Take 10 project credits.
ECP 8776 - Project Credits: Master's Plan B (1.0-18.0 cr)
 
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ECP 5220 - Regulatory Issues in Drug Research
Credits: 2.0 [max 2.0]
Typically offered: Every Fall
Regulatory issues encountered in conducting drug research trials. Performing different aspects of clinical trials. Lectures, readings, small group discussions, homework assignments. prereq: ECP grad student or Pharm.D. professional student or instr consent
ECP 8230 - Principles of Clinical Pharmacology
Credits: 2.0 [max 2.0]
Grading Basis: A-F only
Typically offered: Every Fall
Factors determining drug exposure, drug-receptor pharmacology, drug response. Personalized medicine including drug interactions, obesity, age (geriatrics/pediatrics), critical illness, therapeutic evaluation, drug development. prereq: Grad student in Experimental and Clinical Pharmacology or instr consent
ECP 8983 - Scientific Communications in Experimental and Clinical Pharmacology
Credits: 1.0 [max 1.0]
Typically offered: Every Spring
Introduction of professional development concepts in written and oral scientific communication through lectures, literature readings, and class participation.
ECP 8982 - Inter-Institutional Journal Club in Translational Research
Credits: 1.0 [max 2.0]
Typically offered: Every Fall
This course is structured as an inter-institutional journal club between universities of Minnesota, Pittsburgh, and Kentucky that is focused on translational research in clinical pharmacology. Articles will be discussed on topics such as precision medicine, pharmacokinetics, pharmacometrics, pharmacogenomics, and clinical biomarkers.
ECP 8100 - Seminar
Credits: 1.0 [max 8.0]
Grading Basis: S-N only
Typically offered: Every Fall & Spring
Selected topics in experimental/clinical pharmacology. prereq: ECP grad student or instr consent
PUBH 6450 - Biostatistics I
Credits: 4.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Fall & Spring
This course will cover the fundamental concepts of exploratory data analysis and statistical inference for univariate and bivariate data, including: ? study design and sampling methods, ? descriptive and graphical summaries, ? random variables and their distributions, ? interval estimation, ? hypothesis testing, ? relevant nonparametric methods, ? simple regression/correlation, and ? introduction to multiple regression. There will be a focus on analyzing data using statistical programming software and on communicating the results in short reports. Health science examples from the research literature will be used throughout the course. prereq: [College-level algebra, health sciences grad student] or instr consent
PUBH 6451 - Biostatistics II
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
This course will cover more advanced aspects of statistical analysis methods with a focus on statistical modeling, including: ? two-way ANOVA, ? multiple linear regression, ? logistic regression, ? Poisson regression, ? log binomial and ordinal regression, ? survival analysis methods, including Kaplan-Meier analysis and proportional hazards (Cox) regression, ? power and sample size, and ? survey sampling and analysis. There will be a focus on analyzing data using statistical programming software and on communicating the results in short reports. Health science examples from the research literature will be used throughout the course. prereq: [PubH 6450 with grade of at least B, health sciences grad student] or instr consent
STAT 5101 - Theory of Statistics I
Credits: 4.0 [max 4.0]
Typically offered: Every Fall
Logical development of probability, basic issues in statistics. Probability spaces. Random variables, their distributions and expected values. Law of large numbers, central limit theorem, generating functions, multivariate normal distribution. prereq: (MATH 2263 or MATH 2374 or MATH 2573H), (MATH 2142 or CSCI 2033 or MATH 2373 or MATH 2243)
STAT 5102 - Theory of Statistics II
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
Sampling, sufficiency, estimation, test of hypotheses, size/power. Categorical data. Contingency tables. Linear models. Decision theory. prereq: [5101 or Math 5651 or instr consent]
ECP 8777 - Thesis Credits: Master's
Credits: 1.0 -18.0 [max 50.0]
Grading Basis: No Grade
Typically offered: Every Fall, Spring & Summer
Thesis credits: master's. prereq: Max 18 cr per semester or summer; 10 cr total required [Plan A only]
ECP 8776 - Project Credits: Master's Plan B
Credits: 1.0 -18.0 [max 50.0]
Grading Basis: No Grade
Typically offered: Every Fall, Spring & Summer
Project credits: master's Plan B prereq: Max 18 cr per semester or summer; 10 cr total required (Plan B only)