Twin Cities campus

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Twin Cities Campus

Clinical Research M.S.

School of Public Health - Adm
School of Public Health
Link to a list of faculty for this program.
Contact Information
School of Public Health, MMC 819, A395 Mayo Memorial Building, 420 Delaware Street, Minneapolis, MN 55455 (612-626-3500 OR 1-800-774-8636)
Email: sph-ask@umn.edu
Website: http://www.sph.umn.edu
  • Program Type: Master's
  • Requirements for this program are current for Fall 2024
  • Length of program in credits: 38
  • This program does not require summer semesters for timely completion.
  • Degree: Master of Science
Along with the program-specific requirements listed below, please read the General Information section of this website for requirements that apply to all major fields.
The MS in clinical research is a graduate degree as well as a career development path for physician-scientists, clinical scholars, and biomedical researchers. The clinical research MS program trains students to perform patient-oriented research, develop therapeutic interventions conduct clinical trials, write grants, and develop data analytic skills. The program offers maximum flexibility and it can be completed online and students have varied capstone project opportunities. The School of Public Health is accredited by the Council on Education for Public Health (CEPH).
Program Delivery
  • completely online (all program coursework can be completed online)
Prerequisites for Admission
The preferred undergraduate GPA for admittance to the program is 3.00.
An advanced health professional degree (MD, DDS, DVM, DO, DNP, DC, PharmD, PhD, etc.) or other advanced doctoral degree in a clinical biomedical field from an accredited university.
Other requirements to be completed before admission:
Students must have completed or must be at an advanced stage of their clinical practice training. All applicants should have an identified mentor at the University of Minnesota who will provide them with a research project and guide their research prior to applying for admission. Applicants who are part of a University of Minnesota fellowship or residency program, should in addition, discuss their application with their fellowship or residency director. One of the three required recommendation letters must be from the mentor at the University of Minnesota willing to provide mentorship and access to a research project.
Special Application Requirements:
An official transcript verifying completion of an advanced health professional degree and training sufficient to be eligible for a license to practice. One of the three required recommendation letters and a completed School of Public Health Recommendation form from the clinical director of training supporting the applicant's potential as a clinical researcher.
International applicants must submit score(s) from one of the following tests:
  • TOEFL
    • Internet Based - Total Score: 100
    • Paper Based - Total Score: 600
  • IELTS
    • Total Score: 7.0
  • MELAB
    • Final score: 80
The preferred English language test is Test of English as Foreign Language.
Key to test abbreviations (TOEFL, IELTS, MELAB).
For an online application or for more information about graduate education admissions, see the General Information section of this website.
Program Requirements
Plan B: Plan B requires 38 major credits and 0 credits outside the major. The final exam is oral. A capstone project is required.
Capstone Project:Students can opt to complete a manuscript or a grant proposal for their capstone project. The topic and scope of the project must be approved by the advisor and director of graduate studies.
This program may be completed with a minor.
Use of 4xxx courses towards program requirements is not permitted.
A minimum GPA of 3.00 is required for students to remain in good standing.
At least 1 semesters must be completed before filing a Degree Program Form.
Students must complete both sessions of the University's Responsible Conduct of Research course, validated by ORTTA. Students also must complete the NIH's online training, Protection of Human Research Subjects, validated by electronic certificate upon successful completion. A grade of at least B- must be earned for the core, epidemiology, and clinical trials courses taken on the A-F grade basis. If PUBH 6320 is taken, a grade of at least A- must be earned.
Required Core Courses (16 credits)
Take the following courses:
PUBH 6250 - Foundations of Public Health (2.0 cr)
PUBH 6301 - Fundamentals of Clinical Research (3.0 cr)
PUBH 6310 - Clinical Epidemiology 1 (1.0 cr)
PUBH 6311 - Clinical Epidemiology II (1.0 cr)
PUBH 6450 - Biostatistics I (4.0 cr)
PUBH 6451 - Biostatistics II (4.0 cr)
PUBH 6742 - Ethics in Public Health: Research and Policy (1.0 cr)
Epidemiology Course (3 credits)
Select one of the following courses in consultation with the director of graduate studies.
PUBH 6341 - Epidemiologic Methods I (3.0 cr)
or PUBH 6320 - Fundamentals of Epidemiology (3.0 cr)
Clinical Trials Course (3 credits)
Select one of the following courses in consultation with the director of graduate studies.
PUBH 7420 - Clinical Trials: Design, Implementation, and Analysis (3.0 cr)
or PUBH 7415 - Introduction to Clinical Trials (3.0 cr)
Capstone Project (6 to 10 credits)
Take 6 to 10 credits of PUBH 8394, in consultation with the advisor and director of graduate studies.
PUBH 8394 - Capstone Project: Clinical Research (1.0-10.0 cr)
Electives
Select electives in consultation with the director of graduate studies to meet the 38-credit requirement.
DENT 8114 - Topics in Advanced Periodontology: Literature Review (2.0 cr)
DENT 8120 - Advanced Principles and Techniques of Orofacial Pain Disorders (2.0 cr)
DENT 8121 - Current Literature in TMD and Orofacial Pain (1.0 cr)
ECP 5220 - Regulatory Issues in Drug Research (2.0 cr)
ECP 5620 - Drug Metabolism and Disposition (3.0 cr)
ECP 8100 - Seminar (1.0 cr)
MICA 8013 - Translational Cancer Research (2.0 cr)
NURS 6102 - Family Health Theory (2.0 cr)
NURS 7202 - Moral and Ethical Positions and Actions in Nursing (2.0 cr)
NURS 8152 - Advanced Ethics in Nursing Research and Scholarship (2.0 cr)
NURS 8172 - Theory and Theory Development for Research (3.0 cr)
NURS 8173 - Principles and Methods of Implementing Research (3.0 cr)
NURS 8175 - Quantitative Research Design and Methods (3.0 cr)
PHAR 6224 - Advanced Pharmacogenomics and Precision Medicine (2.0 cr)
PHCL 5111 - Pharmacogenomics (3.0 cr)
PUBH 6108 - Foundations of Global Health (2.0 cr)
PUBH 6181 - Surveillance of Foodborne Diseases and Food Safety Hazards (2.0 cr)
PUBH 6303 - Clinical Research Project Seminar (2.0 cr)
PUBH 6325 - Data Processing with PC-SAS (1.0 cr)
PUBH 6343 - Epidemiologic Methods III (4.0 cr)
PUBH 6348 - Writing Research Grants (2.0 cr)
PUBH 6381 - Genetics in Public Health in the Age of Precision Medicine (2.0 cr)
PUBH 6385 - Epidemiology and Control of Infectious Diseases (2.0 cr)
PUBH 6386 - Cardiovascular Disease Epidemiology and Prevention (2.0 cr)
PUBH 6387 - Cancer Epidemiology (2.0 cr)
PUBH 6389 - Nutritional Epidemiology (2.0 cr)
PUBH 6420 - Introduction to SAS Programming (1.0 cr)
PUBH 6717 - Decision Analysis for Health Care (2.0 cr)
PUBH 6803 - Conducting a Systematic Literature Review (3.0 cr)
PUBH 6863 - Understanding Health Care Quality (2.0 cr)
PUBH 6864 - Conducting Health Outcomes Research (3.0 cr)
PUBH 7430 - Statistical Methods for Correlated Data (3.0 cr)
PUBH 7440 - Introduction to Bayesian Analysis (3.0 cr)
PUBH 7445 - Statistics for Human Genetics and Molecular Biology (3.0 cr)
PUBH 7450 - Survival Analysis (3.0 cr)
PUBH 7470 - Study Designs in Biomedical Research (3.0 cr)
TMDP 8441 - Seminar in Temporomandibular Disorders & Orofacial Pain (1.0 cr)
VMED 5080 - Problems in Veterinary Epidemiology and Public Health (1.0-3.0 cr)
VMED 5165 - Surveillance of Foodborne Diseases and Food Safety Hazards (2.0 cr)
VMED 8090 - Epidemiology of Zoonoses and Diseases Common to Animals and Humans (3.0 cr)
 
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PUBH 6250 - Foundations of Public Health
Credits: 2.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Fall, Spring & Summer
In this course we will examine values, contexts, principles, and frameworks of public health. We will provide an introduction to public health, consider the history of public health, social/political determinants, impact of health disparities on race, class and gender, moral and legal foundations, public health structures, historical trauma and cultural competence, health and human rights, advocacy and health equity, communication and financing, and the future of public health in the 21st century. Grounded in theory and concepts, we will incorporate core competencies and skills for public health professionals and will focus on developing problem solving and decision-making skills through critical analysis, reflection, case studies, readings, and paper assignments.
PUBH 6301 - Fundamentals of Clinical Research
Credits: 3.0 [max 3.0]
Course Equivalencies: PubH 6301/PubH 6305
Typically offered: Every Fall
Concepts of clinical research design/implementation/analysis. Students will learn skills needed for research in humans.
PUBH 6310 - Clinical Epidemiology 1
Credits: 1.0 [max 1.0]
Typically offered: Every Spring
Clinical epidemiology is the science of using population methods to answer individual patient questions. In this course in clinical epidemiology, I will cover the design of epidemiological studies and the analysis and interpretation of epidemiological data in order to answer clinical questions. A variety of study design methods including cohort, case-control, and cross-sectional study designs will be taught. The design and analysis of clinical trials are covered in-depth by other courses (e.g. PUBH 7420 and 7415) and hence are not covered here. This course is intended for MS students majoring in clinical research. If you are in the clinical research certificate program and have an MD, you can enroll in this course. If you are in the clinical research certificate program and do NOT have an MD, please contact the instructor for permission prior to enrolling. Others including those in MPH programs in the School of Public Health and other interested students should contact the instructor for permission prior to enrolling. If you have already studied advanced methods in epidemiology or biostatistics or completed Epi Methods II (PUBH 6342) or more advanced Epidemiology courses, please do not take this 1-credit course since there will be redundant material. You may be interested instead in Clinical Epidemiology II, which focuses on more clinical aspects including prognosis, diagnosis, treatment, and prevention.
PUBH 6311 - Clinical Epidemiology II
Credits: 1.0 [max 1.0]
Typically offered: Every Spring
Clinical epidemiology is the science of using population methods to answer individual patient questions. This course in clinical epidemiology will cover the design of epidemiological studies and the analysis and interpretation of epidemiological data in order to answer clinical questions. Clinical Epidemiology II will cover concepts related to prognosis, diagnosis, treatment, and prevention. This course is intended for MS students majoring in clinical research. If you are in the clinical research certificate program and have an MD, please contact the instructor for permission. Students in PhD programs in the School of Public Health are welcome to enroll as long as they meet the course requirements. This course is not suitable for MPH students. COURSE PREREQUISITES ? Fundamentals of Epidemiology (PUBH 6320; grade of B- or higher) OR Epidemiological Methods I (PUBH 6341; grade B- or higher), or equivalent. ? Clinical Epidemiology I (PUBH 6310; grade B- or higher) OR Epidemiological Methods II (PUBH 6342; grade B- or higher), or equivalent. ? Biostatistics Literacy (PUBH 6414; grade of B- or higher) OR Biostatistics I (PUBH 6450; grade B- or higher), or equivalent.
PUBH 6450 - Biostatistics I
Credits: 4.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Fall & Spring
This course will cover the fundamental concepts of exploratory data analysis and statistical inference for univariate and bivariate data, including: ? study design and sampling methods, ? descriptive and graphical summaries, ? random variables and their distributions, ? interval estimation, ? hypothesis testing, ? relevant nonparametric methods, ? simple regression/correlation, and ? introduction to multiple regression. There will be a focus on analyzing data using statistical programming software and on communicating the results in short reports. Health science examples from the research literature will be used throughout the course. prereq: [College-level algebra, health sciences grad student] or instr consent
PUBH 6451 - Biostatistics II
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
This course will cover more advanced aspects of statistical analysis methods with a focus on statistical modeling, including: ? two-way ANOVA, ? multiple linear regression, ? logistic regression, ? Poisson regression, ? log binomial and ordinal regression, ? survival analysis methods, including Kaplan-Meier analysis and proportional hazards (Cox) regression, ? power and sample size, and ? survey sampling and analysis. There will be a focus on analyzing data using statistical programming software and on communicating the results in short reports. Health science examples from the research literature will be used throughout the course. prereq: [PubH 6450 with grade of at least B, health sciences grad student] or instr consent
PUBH 6742 - Ethics in Public Health: Research and Policy
Credits: 1.0 [max 1.0]
Grading Basis: A-F only
Typically offered: Every Fall, Spring & Summer
Introduction to ethical issues in public health research/policy. Ethical analysis. Recognizing/analyzing moral issues.
PUBH 6341 - Epidemiologic Methods I
Credits: 3.0 [max 3.0]
Course Equivalencies: PubH 6320PubH /6341
Grading Basis: A-F only
Typically offered: Every Fall
Introduction to epidemiologic concepts and methods: (1) Study design (randomized trials and observational studies); (2) Measures of exposure-disease association; (3) Casual inference and bias; (4) Confounding and effect modification.
PUBH 6320 - Fundamentals of Epidemiology
Credits: 3.0 [max 3.0]
Grading Basis: A-F only
Typically offered: Every Fall, Spring & Summer
This course provides an understanding of basic methods and tools used by epidemiologists to study the health of populations.
PUBH 7420 - Clinical Trials: Design, Implementation, and Analysis
Credits: 3.0 [max 3.0]
Typically offered: Every Spring
Introduction to and methodology of randomized clinical trials. Design issues, sample size, operational details, interim monitoring, data analysis issues, overviews. prereq: 6451 or concurrent registration is required (or allowed) in 6451 or 7406 or instr consent
PUBH 7415 - Introduction to Clinical Trials
Credits: 3.0 [max 3.0]
Course Equivalencies: PubH 3415/PubH 7415
Typically offered: Every Fall & Summer
Hypotheses/endpoints, choice of intervention/control, ethical considerations, blinding/randomization, data collection/monitoring, sample size, analysis, writing. Protocol development, group discussions. prereq: 6414 or 6450 or one semester graduate-level introductory biostatistics or statistics or instr consent
PUBH 8394 - Capstone Project: Clinical Research
Credits: 1.0 -10.0 [max 10.0]
Grading Basis: S-N only
Typically offered: Every Fall, Spring & Summer
Directed research toward completion of culminating experience project in clinical research.
DENT 8114 - Topics in Advanced Periodontology: Literature Review
Credits: 2.0 [max 2.0]
Grading Basis: A-F only
Typically offered: Summer Odd Year
State-of-the-art information on a variety of topics concerning risk factors and therapeutic modalities for periodontal disease.
DENT 8120 - Advanced Principles and Techniques of Orofacial Pain Disorders
Credits: 2.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Every Spring
Interdisciplinary study of theory, principles, epidemiology, mechanisms associated with TMJ/craniofacial pain disorders. Basis for scientific understanding of diagnostic/management strategies. prereq: Participation in TMJ, orofacial pain advanced education program
DENT 8121 - Current Literature in TMD and Orofacial Pain
Credits: 1.0 [max 1.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall, Spring & Summer
Review of current literature/how it relates to past literature. Theories on pain, philosophies of management.
ECP 5220 - Regulatory Issues in Drug Research
Credits: 2.0 [max 2.0]
Typically offered: Every Fall
Regulatory issues encountered in conducting drug research trials. Performing different aspects of clinical trials. Lectures, readings, small group discussions, homework assignments. prereq: ECP grad student or Pharm.D. professional student or instr consent
ECP 5620 - Drug Metabolism and Disposition
Credits: 3.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Spring Odd Year
Oxidatative/conjugative enzymes systems involved in human drug metabolism/disposition. Various in vitro models used to evaluate drug metabolism or chemical entity, pros/cons of each. Factors involved in conducting in vivo studies. Components used to predict in vivo drug disposition from in vivo studies. prereq: Grad student or instr consent
ECP 8100 - Seminar
Credits: 1.0 [max 8.0]
Grading Basis: S-N only
Typically offered: Every Fall & Spring
Selected topics in experimental/clinical pharmacology. prereq: ECP grad student or instr consent
MICA 8013 - Translational Cancer Research
Credits: 2.0 [max 2.0]
Grading Basis: A-F or Aud
Typically offered: Every Spring
Clinical issues in cancer research. Discuss translational research projects as they pertain to a variety of cancers. prereq: 8004 or instr consent
NURS 6102 - Family Health Theory
Credits: 2.0 [max 2.0]
Grading Basis: A-F only
Typically offered: Every Fall
Emerging theory in family nursing science, related theories. Research on family systems for structuring systemic framework to examine clinical problems related to family health care. Applies family health theories to selected phenomena of interest to health care. prereq: 6200 or instr consent
NURS 7202 - Moral and Ethical Positions and Actions in Nursing
Credits: 2.0 [max 2.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall & Spring
Normative ethics and theoretical underpinnings for positions taken. Implications for subsequent action. Morally defensible positions on health-related issues, corresponding actions from perspective of nursing.
NURS 8152 - Advanced Ethics in Nursing Research and Scholarship
Credits: 2.0 [max 3.0]
Grading Basis: A-F only
Typically offered: Every Spring
Students will analyze values underlying concepts and discourses of health, disease, risk, and use of health care technologies. They will analyze central ethical issues in nursing research, scholarship, and research integrity as part of ethics training required to conduct research. prereq: Nursing PhD student or permission of faculty
NURS 8172 - Theory and Theory Development for Research
Credits: 3.0 [max 3.0]
Typically offered: Periodic Fall & Spring
Paradigms in nursing/health, associated methods of scientific/scholarly inquiry. Inductive/deductive techniques for theory development Theory-testing using data obtained under controlled conditions. prereq: Doctoral student
NURS 8173 - Principles and Methods of Implementing Research
Credits: 3.0 [max 3.0]
Course Equivalencies: Nurs 8173/SAPh 8173
Typically offered: Every Spring
Integrates scientific, statistical, and practical aspects of research. Inter-relationships among design, sample selections, subject access, human subjects requirements, instrument selection and evaluation, data management, analyses plans, grant writing, and research career issues. Field experiences required. prereq: 8114 or other 8xxx grad research methods course, 2 grad stat courses;
NURS 8175 - Quantitative Research Design and Methods
Credits: 3.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall
Designs for quantitative description and quasi-experimental/experimental evaluation of scientific problems across domain of nursing. Evaluation of logic of design/attribution of causality from health and social science perspectives. prereq: [PhD student in nursing, advanced applied statistics] or instr consent
PHAR 6224 - Advanced Pharmacogenomics and Precision Medicine
Credits: 2.0 [max 2.0]
Grading Basis: A-F only
Typically offered: Every Spring
This course is for individuals wanting advanced knowledge in PGx and an introduction to the broader field of precision medicine. It consists of lectures, homework assignments and class discussions designed to introduce precision medicine as it relates to the impact of genetic variation on health and the advanced practice of pharmacogenomics. Students will learn diagnostic methods to identify germline and somatic mutations, how algorithms and equations are used for predictions and the relationships between genes and environment. How these concepts apply in the clinical settings, forecast health and drug response will be presented. Emerging tools in genetics and pharmacogenomics will be presented. The course will also address clinical implementation and the ethical, legal, and social issues presented by precision medicine and PGx. Prerequisite: 3rd year PharmD student, graduate student in healthcare or related program, or equivalent experience or instructor consent
PHCL 5111 - Pharmacogenomics
Credits: 3.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Every Spring
Human genetic variation, its implications. Functional genomics, pharmacogenomics, toxicogenomics, proteomics. Interactive, discussion-based course. prereq: Grad student or instr consent Keywords: Pharmacology, Pharmacogenomics, Toxicogenomics, Proteomics, Genetics, Drug
PUBH 6108 - Foundations of Global Health
Credits: 2.0 [max 2.0]
Grading Basis: A-F only
Typically offered: Every Fall
This course provides an introduction to key principles and topics in global health including measures of global burden of disease, identification of key health problems around the world and the main determinants, health systems and international public health organizations. In addition, we will discuss cross-cutting and timely issues in health promotion, disease control programs, and operational research in international settings. Class exercises and discussions will focus on challenging global health problems, and strategies to address them. This course is required for those students enrolled in the School of Public Health Global Health Certificate program, and is also open to other qualified students (see Course Prerequisites). Examples of diseases and illustrations of global health problems in this class will include both infectious and non-infectious diseases and should be of interest to students in various programs.
PUBH 6181 - Surveillance of Foodborne Diseases and Food Safety Hazards
Credits: 2.0 [max 2.0]
Course Equivalencies: PubH 5181/VMed 5165
Typically offered: Every Fall
Principles/methods for surveillance of foodborne diseases. Investigation of outbreaks, assessment of food safety hazards. Focuses on integration of epidemiologic/lab methods.
PUBH 6303 - Clinical Research Project Seminar
Credits: 2.0 [max 2.0]
Grading Basis: S-N only
Typically offered: Every Spring
Students will present their thesis and give and receive feedback. Students must have their project underway.
PUBH 6325 - Data Processing with PC-SAS
Credits: 1.0 [max 1.0]
Typically offered: Every Spring
Introduction to methods for transferring/processing existing data sources. Emphasizes hands-on approach to pre-statistical data processing and analysis with PC-SAS statistical software with a Microsoft Windows operating system.
PUBH 6343 - Epidemiologic Methods III
Credits: 4.0 [max 4.0]
Typically offered: Every Fall
Analysis/interpretation of data from various epidemiological study designs. SAS used to demonstrate epidemiological/statistical concepts in data analysis. prereq: [6342, 6451] with a grade of at least B- or instr consent
PUBH 6348 - Writing Research Grants
Credits: 2.0 [max 2.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall
Focuses on NIH research grants. Mechanisms of grant writing: specific aims, hypotheses, innovation, background, approaches, evaluation analyses, principles of informed consent, budget development, and grant-review process.
PUBH 6381 - Genetics in Public Health in the Age of Precision Medicine
Credits: 2.0 [max 2.0]
Typically offered: Every Fall
Our understanding of human genomic variation and its relationship to health is expanding rapidly. This knowledge is now being translated primarily through the field of ?precision medicine? (finding the right drug for the right person at the right time). Public health, in contrast, seeks to abate the social and environmental factors that lead to disease and health disparities. This course will provide an introduction to the field of public health genomics at this interesting point in its history. Approximately one-half of the course is devoted to Genetic Epidemiology, or the science of detecting genetic risk factors for human disease. The other half of the course will cover public health genomics, including ?precision public health?, genetic screening programs, and the possibilities and pitfalls of direct to consumer marketing of genetic tests. How genomics relates to health equity will be a recurring theme of this course. This is a graduate course designed primarily for Epidemiology MPH and PhD students, and fulfills the ?Epi Of? requirement for the MPH in Epidemiology. Graduate students from other programs are very welcome.
PUBH 6385 - Epidemiology and Control of Infectious Diseases
Credits: 2.0 [max 2.0]
Typically offered: Every Spring
Principles and/ methods. Strategies for disease control and prevention, including immunization. Relevance of modes of transmission of specific agents for disease spread and prevention. Public health consequences of infectious diseases at local, national, and international levels.
PUBH 6386 - Cardiovascular Disease Epidemiology and Prevention
Credits: 2.0 [max 2.0]
Typically offered: Every Spring
The course will provide an introduction to cardiovascular disease (CVD) epidemiology. It is intended to provide a detailed perspective on the well-established risk factors for CVD, as well as an introduction to emerging risk factors. Both observational studies and clinical trials will be discussed. The class will include a main focus on prevention of cardiovascular disease, and national recommendations for treatment and prevention. Several classes will incorporate discussions of new directions and current controversies in CVD. Additionally, the class will introduce students to the CVD research in the Division of Epidemiology and Community Health.
PUBH 6387 - Cancer Epidemiology
Credits: 2.0 [max 2.0]
Typically offered: Fall Odd Year
Epidemiologic aspects of cancer. Theories of carcinogenesis, patterns of incidence and mortality, site-specific risk factors. Issues of cancer control and prevention.
PUBH 6389 - Nutritional Epidemiology
Credits: 2.0 [max 2.0]
Typically offered: Fall Even Year
Nutrition/disease relationships through application of epidemiologic methods. Characterization of various exposures to food/nutrient intakes, biological basis for nutrition/disease relationships. Studies of specific chronic diseases and nutritional intake. Design/interpretation of studies using nutritional measures. prereq: [[6320 or 6330 or 6341], [Epidemiology MPH or Public Health Nutrition MPH or Epidemiology PhD student]] or instr consent
PUBH 6420 - Introduction to SAS Programming
Credits: 1.0 [max 1.0]
Typically offered: Periodic Fall & Summer
Use of SAS for analysis of biomedical data. Data manipulation/description. Basic statistical analyses (t-tests, chi-square, simple regression).
PUBH 6717 - Decision Analysis for Health Care
Credits: 2.0 [max 2.0]
Typically offered: Every Fall
Introduction to methods/range of applications of decision analysis and cost-effectiveness analysis in health care technology assessment, medical decision making, and health resource allocation.
PUBH 6803 - Conducting a Systematic Literature Review
Credits: 3.0 [max 3.0]
Grading Basis: OPT No Aud
Typically offered: Every Spring
Project-based class to develop systematic review skills for evidence-based practice. Draws from AHRQ and Cochrane systematic review methodology; supported by examples from the Minnesota Evidence-based Practice Center. Use for master?s thesis, dissertation, or to support research proposals. Prereq: research study design or epidemiology.
PUBH 6863 - Understanding Health Care Quality
Credits: 2.0 [max 2.0]
Grading Basis: A-F only
Typically offered: Every Fall
Introduction to assessing/assuring quality of care. Emphasizes both process and outcomes approaches, paralleling interest in appropriateness/effectiveness of care. Issues around creating needed behavioral changes.
PUBH 6864 - Conducting Health Outcomes Research
Credits: 3.0 [max 3.0]
Typically offered: Every Spring
Major concepts/principles in conducting health outcomes research that evaluates medical care. Developing study designs matched to research questions. Frequently used study designs. Evaluating health outcomes. Analytical approaches. prereq: Introductory course in epidemiology or health services research methods or instr consent
PUBH 7430 - Statistical Methods for Correlated Data
Credits: 3.0 [max 3.0]
Typically offered: Every Fall
Correlated data arise in many situations, particularly when observations are made over time and space or on individuals who share certain underlying characteristics. This course covers techniques for exploring and describing correlated data, along with statistical methods for estimating population parameters (mostly means) from these data. The focus will be primarily on generalized linear models (both with and without random effects) for normally and non-normally distributed data. Wherever possible, techniques will be illustrated using real-world examples. Computing will be done using R and SAS. prereq: Regression at the level of PubH 6451 or PubH 7405 or Stat 5302. Familiarity with basic matrix notation and operations (multiplication, inverse, transpose). Working knowledge of SAS or R (PubH 6420).
PUBH 7440 - Introduction to Bayesian Analysis
Credits: 3.0 [max 3.0]
Typically offered: Every Spring
Introduction to Bayesian methods. Comparison with traditional frequentist methods. Emphasizes data analysis via modern computing methods: Gibbs sampler, WinBUGS software package. prereq: [[7401 or STAT 5101 or equiv], [public health MPH or biostatistics or statistics] grad student] or instr consent
PUBH 7445 - Statistics for Human Genetics and Molecular Biology
Credits: 3.0 [max 3.0]
Typically offered: Every Spring
Introduction to statistical problems arising in molecular biology. Problems in physical mapping (radiation hybrid mapping, DDP), genetic mapping (pedigree analysis, lod scores, TDT), biopolymer sequence analysis (alignment, motif recognition), and micro array analysis. prereq: [6450, [6451 or equiv]] or instr consent; background in molecular biology recommended
PUBH 7450 - Survival Analysis
Credits: 3.0 [max 3.0]
Typically offered: Every Spring
Statistical methodologies in analysis of survival data. Kaplan-Meier estimator, Cox's proportional hazards multiple regression model, time-dependent covariates, analysis of residuals, multiple failure outcomes. Typical biomedical applications, including clinical trials and person-years data. prereq: 7405, [STAT 5101 or STAT 8101]
PUBH 7470 - Study Designs in Biomedical Research
Credits: 3.0 [max 3.0]
Typically offered: Every Spring
Diagnostic medicine, including methods for ROC curve. Bioassays. Early-phase clinical trials, methods including dose escalation, toxicity, and monitoring. Quality of life. prereq: [[6450, 6451] or equiv], [grad student in biostatistics or statistics or clinical research], familiarity with SAS
TMDP 8441 - Seminar in Temporomandibular Disorders & Orofacial Pain
Credits: 1.0 [max 1.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall, Spring & Summer
Advanced topics on theories and application of recently developed techniques of data collection, diagnostic strategies, and management.
VMED 5080 - Problems in Veterinary Epidemiology and Public Health
Credits: 1.0 -3.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall & Spring
Individual study on problem of interest to epidemiology or public health student.
VMED 5165 - Surveillance of Foodborne Diseases and Food Safety Hazards
Credits: 2.0 [max 2.0]
Course Equivalencies: PubH 5181/VMed 5165
Typically offered: Every Spring
Principles/methods for surveillance of foodborne diseases. Investigation of outbreaks. Assessment of food safety hazards. Focuses on integration of epidemiologic/lab methods. prereq: [PUBH 5330, [professional school or grad student]] or instr consent
VMED 8090 - Epidemiology of Zoonoses and Diseases Common to Animals and Humans
Credits: 3.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall & Spring
Major human zoonotic diseases, methods of transmission, diagnosis, control, and prevention. prereq: Epidemiology and infectious disease course or instr consent