Twin Cities campus

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Twin Cities Campus

Comparative and Molecular Biosciences M.S.

College of Veterinary Medicine - Adm
College of Veterinary Medicine
Link to a list of faculty for this program.
Contact Information
College of Veterinary Medicine, 1365 Gortner Avenue, Room 443 VMC, Saint Paul, MN 55108 (612-625-3770; fax: 612-626-2825)
  • Program Type: Master's
  • Requirements for this program are current for Fall 2014
  • Length of program in credits: 30
  • This program requires summer semesters for timely completion.
  • Degree: Master of Science
Along with the program-specific requirements listed below, please read the General Information section of this website for requirements that apply to all major fields.
The mission of the Comparative and Molecular Biosciences (CMB) program is to train outstanding scientists in the basic mechanisms of animal and human health and disease. The CMB program is transdisciplinary, bringing together basic, applied, and clinical scientists from a number of departments to provide students with individualized, cutting-edge biomedical research training. Areas of emphasis include genetic and infectious diseases, and comparative aspects of biology and pathology across animal species and humans. Students receive scientific training that prepares them for careers as independent investigators and educators in academia, industry, and government. The CMB program focuses on health that spans a wide range of species, from laboratory animal, companion animal, and livestock species to humans, and is unique within the University of Minnesota. Note: The primary emphasis of the CMB program is the training of doctoral students; however, a small number of individuals complete a master's degree. The purpose of the master's degree is to provide technical training and scientific competence in the basic mechanisms of animal and human health and disease.
Program Delivery
  • via classroom (the majority of instruction is face-to-face)
Prerequisites for Admission
The preferred undergraduate GPA for admittance to the program is 3.25.
A bachelor's degree in a biological or basic science is required. Previous laboratory experience is strongly preferred.
Other requirements to be completed before admission:
Applicants must submit a C.V. or résumé; three letters of recommendation from persons familiar with their scholarship and research potential; and a statement of any research experience, as well as career interests, goals, and objectives.
Special Application Requirements:
Submission of all application materials by December 15 is required to ensure consideration for fall semester admission.
Applicants must submit their test score(s) from the following:
  • GRE
International applicants must submit score(s) from one of the following tests:
  • TOEFL
    • Internet Based - Total Score: 79
    • Internet Based - Writing Score: 21
    • Internet Based - Reading Score: 19
    • Paper Based - Total Score: 550
  • IELTS
    • Total Score: 6.5
  • MELAB
    • Final score: 80
The preferred English language test is Test of English as Foreign Language.
Key to test abbreviations (GRE, TOEFL, IELTS, MELAB).
For an online application or for more information about graduate education admissions, see the General Information section of this website.
Program Requirements
Plan A: Plan A requires 20 major credits, 0 credits outside the major, and 10 thesis credits. The final exam is written and oral.
This program may be completed with a minor.
Use of 4xxx courses toward program requirements is permitted under certain conditions with adviser approval.
A minimum GPA of 3.00 is required for students to remain in good standing.
The M.S. requires a core curriculum of fundamental coursework and laboratory experiences. Students complete a minimum of 20 course credits and 10 thesis credits; the thesis is based on original laboratory research.
Required Courses
CMB 8134 - Ethical Conduct of Animal Research (3.0 cr)
CMB 8202 - Mechanisms of Animal Health and Disease II (3.0 cr)
CMB 8303 - Comparative Models of Disease (2.0 cr)
CMB 8550 - Comparative and Molecular Biosciences Seminar (1.0 cr)
CMB 8560 - Research and Literature Reports (1.0 cr)
Statistics
CMB 5200 - Statistical Genetics and Genomics (4.0 cr)
or PUBH 6450 - Biostatistics I (4.0 cr)
or STAT 5021 - Statistical Analysis (4.0 cr)
or STAT 5031 {Inactive} (4.0 cr)
or STAT 5302 - Applied Regression Analysis (4.0 cr)
or STAT 5303 - Designing Experiments (4.0 cr)
or STAT 5421 - Analysis of Categorical Data (3.0 cr)
 
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· College of Veterinary Medicine

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CMB 8134 - Ethical Conduct of Animal Research
Credits: 3.0 [max 3.0]
Course Equivalencies: AnSc 8134/CMB 8134/VMed 8134
Typically offered: Every Fall
Ethical considerations in the use of animal subjects in agricultural, veterinary, and biomedical research. Federal, state, and University guidelines relating to proper conduct for acquisition and use of animals for laboratory, observational, epidemiological, and clinical research. Regulatory requirements. Bases for proper conduct. Societal impact on scientific investigations utilizing animal subjects.
CMB 8202 - Mechanisms of Animal Health and Disease II
Credits: 3.0 [max 3.0]
Grading Basis: A-F only
Typically offered: Every Fall
Multi-perspective approach to critically evaluating journal articles, as done for peer-reviewed journals. Aspects of host/pathogen interactions, including molecular/genetic mechanisms of host resistance/pathogenesis.
CMB 8303 - Comparative Models of Disease
Credits: 2.0 [max 2.0]
Grading Basis: A-F only
Typically offered: Every Spring
Disease processes in organ systems. Examples of animal models. Comparative medicine. Clinical relevance of problem/disease. Animal models used to study disease process/problem. Lectures. prereq: Enrollment in a biological sciences grad program or instr consent
CMB 8550 - Comparative and Molecular Biosciences Seminar
Credits: 1.0 [max 8.0]
Grading Basis: S-N or Aud
Typically offered: Every Fall & Spring
Student/faculty presentations of their own research or a directed topic. prereq: Biol sciences grad student
CMB 8560 - Research and Literature Reports
Credits: 1.0 [max 2.0]
Grading Basis: S-N or Aud
Typically offered: Every Fall & Spring
Current developments in cellular and molecular mechanisms of animal health and disease.
CMB 5200 - Statistical Genetics and Genomics
Credits: 4.0 [max 4.0]
Grading Basis: A-F or Aud
Typically offered: Fall Even Year
Statistical issues in genomics. Gene detection, including statistical analysis/designs for linkage study and for mapping quantitative trait loci. Linkage analysis using pedigree data for codominant/dominant markers. Using radiation hybrid mapping and single cell typing. Design issues in linkage analysis, parentage testing, and marker polymorphism.
PUBH 6450 - Biostatistics I
Credits: 4.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Fall & Spring
This course will cover the fundamental concepts of exploratory data analysis and statistical inference for univariate and bivariate data, including: ? study design and sampling methods, ? descriptive and graphical summaries, ? random variables and their distributions, ? interval estimation, ? hypothesis testing, ? relevant nonparametric methods, ? simple regression/correlation, and ? introduction to multiple regression. There will be a focus on analyzing data using statistical programming software and on communicating the results in short reports. Health science examples from the research literature will be used throughout the course. prereq: [College-level algebra, health sciences grad student] or instr consent
STAT 5021 - Statistical Analysis
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
Intensive introduction to statistical methods for graduate students needing statistics as a research technique. prereq: college algebra or instr consent; credit will not be granted if credit has been received for STAT 3011
STAT 5302 - Applied Regression Analysis
Credits: 4.0 [max 4.0]
Typically offered: Every Fall, Spring & Summer
Simple, multiple, and polynomial regression. Estimation, testing, prediction. Use of graphics in regression. Stepwise and other numerical methods. Weighted least squares, nonlinear models, response surfaces. Experimental research/applications. prereq: 3032 or 3022 or 4102 or 5021 or 5102 or instr consent Please note this course generally does not count in the Statistical Practice BA or Statistical Science BS degrees. Please consult with a department advisor with questions.
STAT 5303 - Designing Experiments
Credits: 4.0 [max 4.0]
Typically offered: Every Fall, Spring & Summer
Analysis of variance. Multiple comparisons. Variance-stabilizing transformations. Contrasts. Construction/analysis of complete/incomplete block designs. Fractional factorial designs. Confounding split plots. Response surface design. prereq: 3022 or 3032 or 3301 or 4102 or 5021 or 5102 or instr consent
STAT 5421 - Analysis of Categorical Data
Credits: 3.0 [max 3.0]
Typically offered: Every Fall & Spring
Varieties of categorical data, cross-classifications, contingency tables. Tests for independence. Combining 2x2 tables. Multidimensional tables/loglinear models. Maximum-likelihood estimation. Tests for goodness of fit. Logistic regression. Generalized linear/multinomial-response models. prereq: STAT 3022 or 3032 or 3301 or 5302 or 4051 or 8051 or 5102 or 4102