Twin Cities campus
 
Twin Cities Campus

Stem Cell Biology Minor

Stem Cell Institute
Medical School
Link to a list of faculty for this program.
Contact Information
Department of Stem Cell Biology Institute, 2001 6th Street SE, Mail Code 2873, Minneapolis, MN 55455-3007 (612-625-0602; fax: 612-624-2436)
  • Program Type: Graduate minor related to major
  • Requirements for this program are current for Fall 2019
  • Length of program in credits (doctoral): 12
  • This program does not require summer semesters for timely completion.
The stem cell biology minor is available to PhD students in relevant programs such as MCDB&G, MiCaB, pharmacology, microbiology, bio-engineering, or a medical or veterinary medicine school program, and who have an interest in stem cell biology. It offers training in stem cell biology, which is a rapidly growing interdisciplinary field that rests on foundations provided by molecular, cellular, and developmental biology. Students will take lecture and seminar courses, interact with members of the Stem Cell Institute through participation in research seminar and journal clubs, and conduct stem cell research in the laboratory of a stem cell biology graduate program faculty member.
Program Delivery
  • via classroom (the majority of instruction is face-to-face)
Prerequisites for Admission
Special Application Requirements:
Applicants must be admitted to a Ph.D. program and obtain approval from the Stem Cell Biology director of graduate studies.
For an online application or for more information about graduate education admissions, see the General Information section of this website.
Program Requirements
Use of 4xxx courses toward program requirements is permitted under certain conditions with adviser approval.
In addition to course requirements, the student's research project must be done in the lab of a Stem Cell Biology faculty member; therefore, students must obtain approval from the Stem Cell Biology director of graduate studies prior to declaring the minor. The minimum GPA for minor field coursework is 3.00.
Program Sub-plans
Students are required to complete one of the following sub-plans.
Students may not complete the program with more than one sub-plan.
Doctoral
Required Courses (5 credits)
Take the following required courses on the A/F grade basis.
SCB 5054 - Stem Cell Institute Research Seminar and Journal Club (2.0 cr)
SCB 8181 - Stem Cell Biology (3.0 cr)
Electives (7 credits)
Select at least seven elective credits in consultation with the Stem Cell Biology director of graduate studies to complete the 12-credit minimum. Elective courses should be taken on the A/F grade basis. Courses required to meet the student's major field requirement cannot be applied to the minor.
Take 7 or more credit(s) from the following:
· BIOC 5213 - Selected Topics in Molecular Biology (3.0 cr)
· BIOC 8007 - Molecular Biology of DNA (2.0 cr)
· BIOC 8008 - Molecular Biology of RNA (2.0 cr)
· BIOC 8401 - Ethics, Public Policy, and Careers in Molecular and Cellular Biology (1.0 cr)
· BMEN 5041 - Tissue Engineering (3.0 cr)
· BMEN 5351 - Cell Engineering (3.0 cr)
· BTHX 5000 - Topics in Bioethics (1.0-4.0 cr)
· BTHX 5100 - Introduction to Clinical Ethics (3.0 cr)
· BTHX 5210 - Ethics of Human Subjects Research (3.0 cr)
· BTHX 5325 - Biomedical Ethics (3.0 cr)
· BTHX 5400 - Intro Ethics in Hlth Policy (3.0 cr)
· BTHX 8000 - Advanced Topics in Bioethics (1.0-4.0 cr)
· CSCI 5461 - Functional Genomics, Systems Biology, and Bioinformatics (3.0 cr)
· CSCI 5465 - Introduction to Computing for Biologists (3.0 cr)
· GCD 5005 - Computer Programming for Biology (3.0 cr)
· GCD 5036 - Molecular Cell Biology (3.0 cr)
· GCD 8008 - Mammalian Gene Transfer and Genome Engineering (2.0 cr)
· GCD 8131 - Advanced Molecular Genetics and Genomics (3.0 cr)
· GCD 8151 - Cellular Biochemistry and Cell Biology (2.0-4.0 cr)
· GCD 8161 - Advanced Cell Biology and Development (2.0 cr)
· MICA 8003 - Immunity and Immunopathology (4.0 cr)
· MICA 8004 - Cellular and Cancer Biology (4.0 cr)
· MICA 8014 - Small RNA Biology (2.0 cr)
· MILI 6235 - Pharmaceutical Industry: Business and Policy (2.0 cr)
· MILI 6726 - Medical Device Industry: Business and Public Policy (2.0 cr)
· MILI 6990 - The Health Care Marketplace (2.0 cr)
· MILI 6995 - Medical Industry Valuation Laboratory (2.0 cr)
· NSC 8211 - Developmental Neurobiology (4.0 cr)
· PHCL 5110 - Introduction to Pharmacology (3.0 cr)
· PHCL 5112 - A Graduate Toolkit I: An Introduction to the Scientific Research Lab (1.0 cr)
· PHSL 8242 - Professional Skills Development for Biomedical Scientists (2.0 cr)
· PSY 5063 - Introduction to Functional MRI (3.0 cr)
· PUBH 6450 - Biostatistics I (4.0 cr)
· PUBH 6451 - Biostatistics II (4.0 cr)
 
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SCB 5054 - Stem Cell Institute Research Seminar and Journal Club
Credits: 2.0 [max 6.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall & Spring
Students attend weekly Stem Cell Institute research seminars and journal clubs, write brief summaries, participate in journal club, and present original research paper. prereq: Acceptance into stem cell biology [master's prog or PhD minor prog] or instr consent
SCB 8181 - Stem Cell Biology
Credits: 3.0 [max 3.0]
Course Equivalencies: 01725
Typically offered: Every Fall
Stem cell research and its applications. Critical analysis, written summaries/critiques, oral presentations. prereq: [[GCD 4034], [GCD 4161]] or equiv or instr consent
BIOC 5213 - Selected Topics in Molecular Biology
Credits: 3.0 [max 3.0]
Grading Basis: A-F only
Typically offered: Every Fall
Cutting edge areas in molecular biology. Topics focus on the "3 R's" of DNA: repair, replication, and recombination. Faculty who are experts in these areas teach modules on specific topics, including discussion of their research interests. prereq: 4332 or 8002 or [3021, BIOL 4003] or instr consent
BIOC 8007 - Molecular Biology of DNA
Credits: 2.0 [max 2.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall
Structure and organization of genes. Replication. Transcription. Epigenetic modification of chromatin. Genome editing. Deep sequencing.Cellular adhesion mechanisms.
BIOC 8008 - Molecular Biology of RNA
Credits: 2.0 [max 2.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall
Translation. RNA editing. Epigenetics and long non-coding RNA. MicroRNAs and RNA interference. Pre-mRNA processing.
BIOC 8401 - Ethics, Public Policy, and Careers in Molecular and Cellular Biology
Credits: 1.0 [max 2.0]
Course Equivalencies: 02806
Grading Basis: S-N or Aud
Typically offered: Every Spring
Ethics of scientific investigation from viewpoint of western scientific enterprise. Relationship between science, culture, and public policies. Careers in molecular/cellular biology. Nontraditional career tracks. Invited speakers, case studies, small-group discussions, lectures. prereq: Grad student in [BMBB or MCDBconcurrent registration is required (or allowed) in G]
BMEN 5041 - Tissue Engineering
Credits: 3.0 [max 3.0]
Typically offered: Every Spring
Fundamentals of wound healing and tissue repair; characterization of cell-matrix interactions; case study of engineered tissues, including skin, bone marrow, liver, vessel, and cartilage; regulation of biomaterials and engineered tissues. prereq: CSE upper div or grad student or med student or instr consent
BMEN 5351 - Cell Engineering
Credits: 3.0 [max 3.0]
Typically offered: Periodic Fall & Spring
Engineering approaches to cell-related phenomena important to cell/tissue engineering. Receptor/ligand binding. Trafficking/signaling processes. Applications to cell proliferation, adhesion, and motility. Cell-matrix interactions. prereq: [2401, [2501 or concurrent registration is required (or allowed) in 5501], [MATH 2243 or MATH 2373]] or CSE upper div or grad student or instr consent
BTHX 5000 - Topics in Bioethics
Credits: 1.0 -4.0 [max 8.0]
Typically offered: Every Fall & Spring
Bioethics topics of contemporary interest. Topics specified in Class Schedule.
BTHX 5100 - Introduction to Clinical Ethics
Credits: 3.0 [max 3.0]
Typically offered: Every Fall & Spring
Most frequent ethical problems faced by clinicians, patients/families, and ethics consultants. Forgoing life sustaining treatment, decisional capacity, informed consent, treatment refusals, death/dying, pediatric ethics, reproductive issues, research ethics, psychiatric illness. Real cases.
BTHX 5210 - Ethics of Human Subjects Research
Credits: 3.0 [max 3.0]
Typically offered: Fall Even Year
Issues in ethics of human subjects research. prereq: Grad student or instr consent
BTHX 5325 - Biomedical Ethics
Credits: 3.0 [max 3.0]
Course Equivalencies: 01202
Typically offered: Every Fall & Spring
Major topics/issues in biomedical ethics. Patients' rights/duties, informed consent, confidentiality, ethical issues in medical research, initiation/termination of medical treatment, euthanasia, abortion, allocation of medical resources. prereq: Jr or sr or grad student or instr consent
BTHX 5400 - Intro Ethics in Hlth Policy
Credits: 3.0 [max 3.0]
Typically offered: Spring Even Year
Topics vary to reflect issues of current significance. Relates to law/politics as appropriate but focuses on moral analyses of policy issues. prereq: Grad student or professional student or instr consent
BTHX 8000 - Advanced Topics in Bioethics
Credits: 1.0 -4.0 [max 8.0]
Typically offered: Every Fall & Spring
Advanced study of bioethics topics of contemporary interest. prereq: Grad or professional student
CSCI 5461 - Functional Genomics, Systems Biology, and Bioinformatics
Credits: 3.0 [max 3.0]
Typically offered: Every Spring
Computational methods for analyzing, integrating, and deriving predictions from genomic/proteomic data. Analyzing gene expression, proteomic data, and protein-protein interaction networks. Protein/gene function prediction, Integrating diverse data, visualizing genomic datasets. prereq: 3003 or 4041 or instr consent
CSCI 5465 - Introduction to Computing for Biologists
Credits: 3.0 [max 3.0]
Course Equivalencies: 02621 - CSci 3003/CSci 5465
Typically offered: Fall Odd Year
This course is designed for graduate students in biology or other related sciences that wish to learn fundamental computing skills that will enable them to develop their own computational approaches for meaningful interpretation of scientific data. Students will complete programming assignments in Python and R. No previous programming knowledge assumed. Prereq: Introductory biology course; non-CSE students only.
GCD 5005 - Computer Programming for Biology
Credits: 3.0 [max 3.0]
Typically offered: Every Fall
Computer programming skills with applications in biology. Design/build new computer programs for applications in cell/developmental biology, including modeling of biological processes, advanced data analysis, automated image analysis. prereq: BIOL 4003 or GCD 3033, general statistics course
GCD 5036 - Molecular Cell Biology
Credits: 3.0 [max 3.0]
Typically offered: Every Fall
Analysis of dynamic cellular activities at the molecular level in cell biological fields that are experiencing new research advances not yet reflected in textbooks. Significant emphasis is placed on understanding the experimental basis of our current knowledge of cellular processes through analysis of scientific papers. Project and presentation-based assessments of learning outcomes. prereq: Biol 4004 or instr consent; [sr or grad student] recommended
GCD 8008 - Mammalian Gene Transfer and Genome Engineering
Credits: 2.0 [max 2.0]
Grading Basis: A-F or Aud
Typically offered: Every Spring
Current gene transfer and genome engineering technology. Applications of genetic modifications in animals, particularly transgenic animals and human gene therapy. prereq: instr consent
GCD 8131 - Advanced Molecular Genetics and Genomics
Credits: 3.0 [max 3.0]
Typically offered: Every Fall & Spring
Literature-based course in modern molecular genetic and genomic analysis. Students will gain a deep understanding of the fundamental molecular mechanisms controlling inheritance in biological systems. Students will gain a facility in thinking critically and creatively about how genes work at cellular, organismal, and transgenerational levels. Course instruction emphasizes active-learning approaches, student presentations, and group projects. prereq: [3022 or BIOL 4003], [BIOC 3021 or BIOC 4331] or instr consent
GCD 8151 - Cellular Biochemistry and Cell Biology
Credits: 2.0 -4.0 [max 3.0]
Grading Basis: A-F only
Typically offered: Every Fall
This course introduces graduate students to fundamental concepts of Biochemical Unity (Part 1) and Cell Theory (Part 2). For Part 1, we will discuss matter of life, equilibrium, entropy & law of mass action, two state systems, random walks & diffusion, rate equations of chemical reactions, and explore how they relate to regulation of biological networks (gene regulation and signal transduction). For Part 2 we will focus on properties of biological membranes, membrane trafficking, protein import & degradation, nuclear structures and their function, as well as molecular motors, cytoskeletal dynamics, and mitosis. The course assumes students have had previous undergraduate courses in cell biology, biochemistry and genetics. prereq: [[[4034 or 8121 or BioC 8002], Biol 4004] or BMBB or MCDBG grad student] or instr consent
GCD 8161 - Advanced Cell Biology and Development
Credits: 2.0 [max 3.0]
Grading Basis: A-F only
Typically offered: Every Spring
The advanced cell and developmental biology of embryos, taught through in-depth, comparative analysis of historical and current primary research articles that illustrate developmental mechanisms and experimental approaches in key invertebrate and vertebrate model organisms. prereq:[BMBB or MCDBG grad student] or [GCD 4161, [GCD 8131 or Biol 4003], Biol 4004, and GCD 4034] or instr consent
MICA 8003 - Immunity and Immunopathology
Credits: 4.0 [max 4.0]
Typically offered: Every Fall
Lymphocyte activation, signal transduction in lymphocytes, antigen receptor genetics, antigen presentation, lymphoid anatomy, adaptive immune responses to microbes, immunodeficiency, immunopathology, cytokines, transplantation, autoimmunity. prereq: Upper level undergrad immunology course or instr consent
MICA 8004 - Cellular and Cancer Biology
Credits: 4.0 [max 4.0]
Grading Basis: A-F or Aud
Typically offered: Every Spring
Fundamental concepts in cellular, molecular, and genetic basis of disease. Molecular basis of inflammation and cancer metastasis. Genetic basis for inherited disorders and gene therapy. Molecular mechanisms of pathogenesis. prereq: [One undergrad or grad course each in [biochemistry, cell biology]] or instr consent
MICA 8014 - Small RNA Biology
Credits: 2.0 [max 2.0]
Grading Basis: A-F or Aud
Typically offered: Every Spring
Small RNAs as major regulators of gene/protein expression. MicroRNAs and their potential use in diagnosis/prognosis of various disease conditions, including cancers. Biology of small RNAs and their role in health and disease. prereq: BIOC 8002 or MICA 8004 or equiv or instr consent
MILI 6235 - Pharmaceutical Industry: Business and Policy
Credits: 2.0 [max 2.0]
Prerequisites: MBA student
Grading Basis: A-F only
Typically offered: Every Spring
Business/policy issues specific to pharmaceutical industry. Interdisciplinary perspectives, active involvement by industry leaders.
MILI 6726 - Medical Device Industry: Business and Public Policy
Credits: 2.0 [max 2.0]
Grading Basis: A-F only
Typically offered: Every Fall
This course, with the insight of industry leaders, addresses public-private sector interactions and the business, public policy, regulatory, and technology management issues that concern medical device and biotechnology companies.
MILI 6990 - The Health Care Marketplace
Credits: 2.0 [max 2.0]
Course Equivalencies: 02186 - MILI 5990/MILI 6990
Grading Basis: A-F only
Typically offered: Every Fall & Spring
Survey of trillion dollar medical industry. Physician/hospital services, insurance, pharmaceuticals, medical devices, information technology. Scale, interactions, inter-relationships, market opportunities, barriers. prereq: MBA student
MILI 6995 - Medical Industry Valuation Laboratory
Credits: 2.0 [max 6.0]
Grading Basis: A-F only
Typically offered: Every Fall, Spring & Summer
Interdisciplinary student teams create rapid production market analysis of promising medical technologies/services to determine potential for success in market. Exposure to University innovations, venture firms, inventors. prereq: Grad student
NSC 8211 - Developmental Neurobiology
Credits: 4.0 [max 4.0]
Grading Basis: A-F or Aud
Typically offered: Every Spring
How neuronal types develop. Emphasizes general mechanisms. Experimental data demonstrating mechanisms. prereq: Neuroscience grad student or instr consent
PHCL 5110 - Introduction to Pharmacology
Credits: 3.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall
Basic principles of Pharmacology. Focuses on molecular mechanisms of drug action. prereq: Grad student or instr consent Keywords: Introduction, Pharmacology, Molecular, Drug, Pharmacokinetics, Pharmacodynamics, Protein, Neuropharmacology, Chemotherapy, Pharmacokinetics
PHCL 5112 - A Graduate Toolkit I: An Introduction to the Scientific Research Lab
Credits: 1.0 [max 1.0]
Grading Basis: A-F only
Typically offered: Every Fall
Basic operating principles/techniques of the scientific research lab. Personnel structure, professionalism, authorship/publication. Recombinant protein production/purification, DNA/RNA purification/methods, molecular biology methods, microscopy, model systems/bioinformatics. prereq: instr consent Keywords: Basic Science, Pharmacology, Personnel, Writing, Presentation, Protein, DNA, Molecule, Microscope, Bioinformatics, Drug
PHSL 8242 - Professional Skills Development for Biomedical Scientists
Credits: 2.0 [max 1.0]
Grading Basis: A-F only
Typically offered: Periodic Fall, Spring & Summer
Professional skills development, including critical evaluation of the scientific literature, short oral presentations, development of research project specific aims and grant writing. Students will become familiar with strategies/mechanics of writing a grant proposal, NIH study section grant reviews, scientific presentations, dissecting scientific literature, and PubMed/NIHreporter tools. prereq: instr consent
PSY 5063 - Introduction to Functional MRI
Credits: 3.0 [max 3.0]
Grading Basis: A-F only
Typically offered: Every Fall
How to understand and perform a brain imaging experiment. Theory and practice of functional MRI experimental design, execution, and data analysis. Students develop experimental materials/acquire and analyze their own functional MRI data. Lectures/lab exercises. prereq: Jr or sr or grad or instr consent
PUBH 6450 - Biostatistics I
Credits: 4.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Fall & Spring
Descriptive statistics. Gaussian probability models, point/interval estimation for means/proportions. Hypothesis testing, including t, chi-square, and nonparametric tests. Simple regression/correlation. ANOVA. Health science applications using output from statistical packages. prereq: [College-level algebra, health sciences grad student] or instr consent
PUBH 6451 - Biostatistics II
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
Two-way ANOVA, interactions, repeated measures, general linear models. Logistic regression for cohort and case-control studies. Loglinear models, contingency tables, Poisson regression, survival data, Kaplan-Meier methods, proportional hazards models. prereq: [PubH 6450 with grade of at least B, health sciences grad student] or instr consent