Twin Cities campus
 
Twin Cities Campus

Integrative Biology and Physiology Ph.D.

Integrative Biology and Physiology
Medical School
Link to a list of faculty for this program.
Contact Information
Department of Integrative Biology and Physiology, Jackson Hall 6-125, 321 Church Street SE, Minneapolis, MN 55455 (612-625-5902; fax: 612-301-1543)
  • Program Type: Doctorate
  • Requirements for this program are current for Spring 2020
  • Length of program in credits: 55
  • This program does not require summer semesters for timely completion.
  • Degree: Doctor of Philosophy
Along with the program-specific requirements listed below, please read the General Information section of this website for requirements that apply to all major fields.
Physiology may be defined as the application of mathematics, physics, and chemistry to the study of structure and function in living systems. As such, physiology is a "hybrid" field in which expertise from many other disciplines is ordinarily required and combined. The program emphasizes a quantitative approach to understanding the functions of cells, organs, and systems in living animals. PhD students take a core concentration that provides a broad background in the physiology of membranes, cells, transport, and organ systems. Individualized programs are structured to build on the student's strengths and to fill in gaps that would otherwise be an impediment to specific problem solving. Teaching experience is also available to all students. The graduate program in the Twin Cities has cardiovascular, hypertension and metabolism emphases, although many other areas of specialization are represented. Students can enter the PhD program from the Twin Cities or Duluth campus. Highly qualified individuals with solid quantitative backgrounds are encouraged to apply. In the Twin Cities, prospective students also include people with previous medical training who are already at the University of Minnesota or are considering the University of Minnesota Medical School for residency or fellowship training. Entering PhD students are expected to take a series of laboratory rotations to familiarize themselves with active areas of research within the degree program. The program includes faculty and corresponding research laboratories from the Department of Integrative Biology and Physiology and also the Departments of Medicine; Surgery; Neuroscience; Neurosurgery; Biochemistry, Molecular Biology, and Biophysics; Pharmacology; Physical Medicine and Rehabilitation; Kinesiology; and Animal Science.
Program Delivery
  • via classroom (the majority of instruction is face-to-face)
Prerequisites for Admission
Other requirements to be completed before admission:
An undergraduate degree with at least one year (three quarters or two semesters) of calculus, one year of physics, one year of biology, and two years of chemistry is required. For the minor, a background in mathematics, physics, chemistry and biology acceptable to the graduate faculty is required.
Special Application Requirements:
There are no minimum GPA or GRE score requirements. All applicants need three letters of recommendation. Admission to the program begins in the Fall semester. International applicants must submit score(s) from one of the following tests:
International applicants must submit score(s) from one of the following tests:
  • TOEFL
    • Internet Based - Total Score: 107
    • Internet Based - Writing Score: 21
    • Internet Based - Reading Score: 19
    • Paper Based - Total Score: 625
  • IELTS
    • Total Score: 6.5
Key to test abbreviations (TOEFL, IELTS).
For an online application or for more information about graduate education admissions, see the General Information section of this website.
Program Requirements
31 credits are required in the major.
0 credits are required outside the major.
24 thesis credits are required.
This program may be completed with a minor.
Use of 4xxx courses toward program requirements is permitted under certain conditions with adviser approval.
A minimum GPA of 3.00 is required for students to remain in good standing.
At least 3 semesters must be completed before filing a Degree Program Form.
During the first year, students rotate through three to four laboratories, attend weekly seminars, choose an advisor, and begin a research project. All coursework must be taken A/F and with an earned grade of B or higher unless offered S/N only.
Required Coursework (21 credits)
Take the following courses in consultation with the advisor. Take PHSL 8232 in conjunction with PHSL 5101; 2 credits of PHSL 5701; and 2 credits of PHSL 8294, on an S/N grade basis, at least twice for 4 credits.
ANSC 5700 - Cell Physiology (4.0 cr)
BIOC 8401 - Ethics, Public Policy, and Careers in Molecular and Cellular Biology (1.0 cr)
PHSL 5101 - Human Physiology (5.0 cr)
PHSL 5197 - Stress Physiology (1.0 cr)
PHSL 5701 - Physiology Laboratory (1.0-2.0 cr)
PHSL 8232 - Critical Reading of Journal Articles in Physiology (2.0 cr)
PHSL 8242 - Professional Skills Development for Biomedical Scientists (2.0 cr)
PHSL 8294 - Research in Physiology (1.0-18.0 cr)
PhD Seminar (4 credits)
Take PHSL 5096 at least 4 times for a total of 4 credits.
PHSL 5096 - Integrative Biology and Physiology Research Advances (1.0 cr)
Molecular Biology and Genetic Coursework (3 credits)
Select at least 3 credits from the following, in consultation with the advisor.
BIOC 4331 - Biochemistry I: Structure, Catalysis, and Metabolism in Biological Systems (4.0 cr)
BIOC 4332 - Biochemistry II: Molecular Mechanisms of Signal Transduction and Gene Expression (4.0 cr)
BIOC 6021 - Biochemistry (3.0 cr)
BIOL 4003 - Genetics (3.0 cr)
BIOL 4004 - Cell Biology (3.0 cr)
GCD 5036 - Molecular Cell Biology (3.0 cr)
Biostatistics Coursework (3 credits)
Select at least 3 credits from the following, in consultation with the advisor.
PUBH 6414 - Biostatistical Literacy (3.0 cr)
PUBH 6450 - Biostatistics I (4.0 cr)
PUBH 6451 - Biostatistics II (4.0 cr)
STAT 5021 - Statistical Analysis (4.0 cr)
Thesis Credits (24 credits)
Take 24 credits of doctoral thesis credits.
PHSL 8888 - Thesis Credit: Doctoral (1.0-24.0 cr)
 
More program views..
View college catalog(s):
· Medical School

View PDF Version:
Search.
Search Programs

Search University Catalogs
Related links.

Medical School

Graduate Admissions

Graduate School Fellowships

Graduate Assistantships

Colleges and Schools

One Stop
for tuition, course registration, financial aid, academic calendars, and more
 
ANSC 5700 - Cell Physiology
Credits: 4.0 [max 4.0]
Course Equivalencies: 02671 - AnSc 5700/Phsl 4700/Phsl 5700
Grading Basis: A-F only
Typically offered: Every Fall
Cell Physiology involves the study of control mechanisms involved in maintaining homeostasis with respect to a variety of parameters including regulation of pH, volume, nutrient content, intracellular electrolyte composition, membrane potential, receptor signaling and aspects of intercellular communication. The first half of this team-taught course is organized in a partially on-line format where students learn from on-line materials and then take an on-line quiz each week before meeting with the instructor to review key concepts in class. The second half of the course is presented in lecture format. Student evaluation is based on quiz scores, in-class exams and graded problem sets.
BIOC 8401 - Ethics, Public Policy, and Careers in Molecular and Cellular Biology
Credits: 1.0 [max 2.0]
Grading Basis: S-N or Aud
Typically offered: Every Fall & Spring
Ethics of scientific investigation from viewpoint of western scientific enterprise. Relationship between science, culture, and public policies. Careers in molecular/cellular biology. Nontraditional career tracks. Invited speakers, case studies, small-group discussions, lectures. prereq: Grad student in [BMBB or MCDBconcurrent registration is required (or allowed) in G]
PHSL 5101 - Human Physiology
Credits: 5.0 [max 5.0]
Course Equivalencies: 01821
Typically offered: Every Spring
Survey of human physiology: Cardiovascular, muscle, respiratory, gastrointestinal, nutrition, renal physiology. Integrative, systems approach. Emphasizes normal function. prereq: Grad student
PHSL 5197 - Stress Physiology
Credits: 1.0 [max 1.0]
Grading Basis: A-F only
Typically offered: Every Spring
Journal club format. Meets weekly to examine foundations of stress, historical progress, development of stress, modern stress physiology. Focus on stress-induced pathology with attention to cardiovascular, metabolic, neuroendocrine disorders. prereq: instr consent, grad student standing or physiology undergraduate major are recommended. Undergraduates are strongly encouraged to have taken 3061 or equivalent.
PHSL 5701 - Physiology Laboratory
Credits: 1.0 -2.0 [max 2.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall & Spring
Experiments in physiology. Emphasizes quantitative aspects, including analysis of organ systems. prereq: instr consent
PHSL 8232 - Critical Reading of Journal Articles in Physiology
Credits: 2.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Spring
Integrative physiology, critical reading of current scientific literature related to lecture topics in the Human Physiology course. prereq: concurrent registration is required (or allowed) in PHSL 5101, instr consent
PHSL 8242 - Professional Skills Development for Biomedical Scientists
Credits: 2.0 [max 1.0]
Grading Basis: A-F only
Typically offered: Periodic Fall, Spring & Summer
Professional skills development, including critical evaluation of the scientific literature, short oral presentations, development of research project specific aims and grant writing. Students will become familiar with strategies/mechanics of writing a grant proposal, NIH study section grant reviews, scientific presentations, dissecting scientific literature, and PubMed/NIHreporter tools. prereq: instr consent
PHSL 8294 - Research in Physiology
Credits: 1.0 -18.0 [max 18.0]
Typically offered: Every Fall, Spring & Summer
Directed laboratory research. prereq: Grad cellular and integrative Phsl major, instr consent
PHSL 5096 - Integrative Biology and Physiology Research Advances
Credits: 1.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Fall & Spring
Attend/participate in IBP Fall/Spring seminar series. Seminars given by faculty, invited speakers, students. Exposure to key topics. How to present seminars. prereq: instr consent
BIOC 4331 - Biochemistry I: Structure, Catalysis, and Metabolism in Biological Systems
Credits: 4.0 [max 4.0]
Course Equivalencies: 00467 - BioC 3021/BioC 3022/BioC 4331/
Typically offered: Every Fall & Spring
Advanced survey of structure/catalysis, metabolism/bioenergetics. prereq: (BIOL 1009 or 2003 or equiv) AND (Chem 2302 or CHEM 2081/2085 or equiv)
BIOC 4332 - Biochemistry II: Molecular Mechanisms of Signal Transduction and Gene Expression
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
Advanced survey of molecular biology. Mechanisms of gene action/biological regulation. prereq: 4331 or instr consent
BIOC 6021 - Biochemistry
Credits: 3.0 [max 3.0]
Course Equivalencies: 00467 - BioC 3021/6021/Biol 3021
Typically offered: Every Fall, Spring & Summer
Fundamentals of biochemistry. Structure/function of proteins, nucleic acids, lipids and carbohydrates. Metabolism, regulation of metabolism. Quantitative treatments of chemical equilibria, enzyme catalysis, and bioenergetics. Chemical basis of genetic information flow. prereq: general biology, organic chemistry, instr consent; intended for MBS students
BIOL 4003 - Genetics
Credits: 3.0 [max 3.0]
Course Equivalencies: 00052
Typically offered: Every Fall, Spring & Summer
Genetic information, its transmission from parents to offspring, its expression in cells/organisms, and its course in populations. prereq: Biol 3020 or BioC 3021 or BioC 4331 or grad MSB
BIOL 4004 - Cell Biology
Credits: 3.0 [max 3.0]
Course Equivalencies: 01965 - Biol 4004/GCD 4005W
Typically offered: Every Fall, Spring & Summer
Processes fundamental to cells. Emphasizes eukaryotic cells. Assembly/function of membranes/organelles. Cell division, cell form/movement, intercellular communication, transport, secretion pathways. Cancer cells, differentiated cells. prereq: BIOL 3020 or BIOL 4003 or grad MSB
GCD 5036 - Molecular Cell Biology
Credits: 3.0 [max 3.0]
Typically offered: Every Fall
Analysis of dynamic cellular activities at the molecular level in cell biological fields that are experiencing new research advances not yet reflected in textbooks. Significant emphasis is placed on understanding the experimental basis of our current knowledge of cellular processes through analysis of scientific papers. Project and presentation-based assessments of learning outcomes. prereq: Biol 4004 or instr consent; [sr or grad student] recommended
PUBH 6414 - Biostatistical Literacy
Credits: 3.0 [max 3.0]
Grading Basis: A-F only
Typically offered: Every Fall, Spring & Summer
Develop ability to read/interpret statistical results in primary literature. Minimal calculation. No formal training in any statistical programming software. Biostatistical Literacy will cover the fundamental concepts of study design, descriptive statistics, hypothesis testing, confidence intervals, odds ratios, relative risks, adjusted models in multiple linear, logistic and Poisson regression, and survival analysis. The focus will be when to use a given method and how to interpret the results, not the actual computation or computer programming to obtain results from raw data. prereq: MPH or certificate student or environmental health or instr consent
PUBH 6450 - Biostatistics I
Credits: 4.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Fall & Spring
Descriptive statistics. Gaussian probability models, point/interval estimation for means/proportions. Hypothesis testing, including t, chi-square, and nonparametric tests. Simple regression/correlation. ANOVA. Health science applications using output from statistical packages. prereq: [College-level algebra, health sciences grad student] or instr consent
PUBH 6451 - Biostatistics II
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
Two-way ANOVA, interactions, repeated measures, general linear models. Logistic regression for cohort and case-control studies. Loglinear models, contingency tables, Poisson regression, survival data, Kaplan-Meier methods, proportional hazards models. prereq: [PubH 6450 with grade of at least B, health sciences grad student] or instr consent
STAT 5021 - Statistical Analysis
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
Intensive introduction to statistical methods for graduate students needing statistics as a research technique. prereq: Credit will not be granted if credit has been received for: : 3011; College algebra or instr consent; Stat course recommended
PHSL 8888 - Thesis Credit: Doctoral
Credits: 1.0 -24.0 [max 100.0]
Grading Basis: No Grade
Typically offered: Every Fall, Spring & Summer
(No description) prereq: Max 18 cr per semester or summer; 24 cr required