Twin Cities campus

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Twin Cities Campus

Integrative Biology and Physiology M.S.

Integrative Biology and Physiology
Medical School
Link to a list of faculty for this program.
Contact Information
Department of Integrative Biology and Physiology, Jackson Hall 6-125, 321 Church Street S.E., Minneapolis, MN 55455 (612-625-5902; fax: 612-625-5149)
  • Program Type: Master's
  • Requirements for this program are current for Spring 2020
  • Length of program in credits: 30 to 32
  • This program does not require summer semesters for timely completion.
  • Degree: Master of Science
Along with the program-specific requirements listed below, please read the General Information section of this website for requirements that apply to all major fields.
Note: Students enter the Twin Cities Integrative Biology and Physiology MS program only for exceptional reasons. The Twin Cities graduate program has a cardiovascular emphasis, although other areas of specialization are represented. The program includes faculty and corresponding research laboratories from the Department of Integrative Biology and Physiology and also the Departments of Medicine; Surgery; Neuroscience; Neurosurgery; Biochemistry, Molecular Biology, and Biophysics; Pharmacology; Physical Medicine and Rehabilitation; Kinesiology; and Animal Science.
Program Delivery
  • via classroom (the majority of instruction is face-to-face)
Prerequisites for Admission
The preferred undergraduate GPA for admittance to the program is 3.00.
International applicants must submit score(s) from one of the following tests:
  • TOEFL
    • Internet Based - Total Score: 79
    • Internet Based - Writing Score: 21
    • Internet Based - Reading Score: 19
    • Paper Based - Total Score: 550
  • IELTS
    • Total Score: 6.5
  • MELAB
    • Final score: 80
Key to test abbreviations (TOEFL, IELTS, MELAB).
For an online application or for more information about graduate education admissions, see the General Information section of this website.
Program Requirements
Plan A: Plan A requires 22 major credits, 0 credits outside the major, and 10 thesis credits. The final exam is written and oral.
Plan B: Plan B requires 30 major credits and 0 credits outside the major. The final exam is oral. A capstone project is required.
Capstone Project:The Plan B project, completed under the direction of an IBP faculty member, focuses on an aspect of Physiology.
This program may be completed with a minor.
Use of 4xxx courses toward program requirements is permitted under certain conditions with adviser approval.
A minimum GPA of 2.80 is required for students to remain in good standing.
Twin Cities campus: Students complete the MS degree only under exceptional circumstances.
Required Coursework (15 credits)
Take PHSL 8232 in conjunction with PHSL 5101. Take PHSL 8294, on an S/N grade basis, at least twice for 2 credits.
ANSC 5702 - Cell Physiology (4.0 cr)
PHSL 5101 - Human Physiology (5.0 cr)
PHSL 8232 - Critical Reading of Journal Articles in Physiology (2.0 cr)
PHSL 8294 - Research in Physiology (1.0-18.0 cr)
Molecular Biology and Genetics Coursework (3 credits)
Select at least 3 credits chosen from the following in consultation with the advisor.
BIOC 4331 - Biochemistry I: Structure, Catalysis, and Metabolism in Biological Systems (4.0 cr)
BIOC 4332 - Biochemistry II: Molecular Mechanisms of Signal Transduction and Gene Expression (4.0 cr)
BIOC 6021 - Biochemistry (3.0 cr)
BIOL 4003 - Genetics (3.0 cr)
BIOL 4004 - Cell Biology (3.0 cr)
GCD 5036 - Molecular Cell Biology (3.0 cr)
IBP Seminar Series (4 credits)
Take PHSL 5096 at least 4 times for a minimum of 4 credits.
PHSL 5096 - Integrative Biology and Physiology Research Advances (1.0 cr)
Plan Options
Plan A
Take at least 10 master's thesis credits.
PHSL 8777 - Thesis Credits: Master's (1.0-18.0 cr)
-OR-
Plan B
Electives
Select elective credits in consultation with the advisor to meet the minimum course credit requirement. Coursework may include the following courses:
NUTR 8620 - Advances in Nutrition (2.0 cr)
PHSL 5197 - Stress Physiology (1.0-3.0 cr)
PHSL 5701 - Physiology Laboratory (1.0-2.0 cr)
PHSL 8242 - Professional Skills Development for Biomedical Scientists (2.0 cr)
PUBH 6450 - Biostatistics I (4.0 cr)
PUBH 6451 - Biostatistics II (4.0 cr)
STAT 5021 - Statistical Analysis (4.0 cr)
 
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ANSC 5702 - Cell Physiology
Credits: 4.0 [max 4.0]
Course Equivalencies: AnSc 5702/Phsl 4702/Phsl 5702
Grading Basis: A-F only
Typically offered: Every Fall
Cell Physiology involves the study of control mechanisms involved in maintaining homeostasis with respect to a variety of parameters including regulation of pH, volume, nutrient content, intracellular electrolyte composition, membrane potential, receptor signaling and aspects of intercellular communication. The first half of this team-taught course is organized in a partially on-line format where students learn from on-line materials and then take an on-line quiz each week before meeting with the instructor to review key concepts in class. The second half of the course is presented in lecture format. Student evaluation is based on quiz scores, in-class exams and graded problem sets.
PHSL 5101 - Human Physiology
Credits: 5.0 [max 5.0]
Course Equivalencies: INMD 6814/PHSL 5101
Typically offered: Every Spring
Survey of human physiology: Cardiovascular, muscle, respiratory, gastrointestinal, nutrition, renal physiology. Integrative, systems approach. Emphasizes normal function. prereq: Grad student
PHSL 8232 - Critical Reading of Journal Articles in Physiology
Credits: 2.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Spring
Integrative physiology, critical reading of current scientific literature related to lecture topics in the Human Physiology course. prereq: concurrent registration is required (or allowed) in PHSL 5101, instr consent
PHSL 8294 - Research in Physiology
Credits: 1.0 -18.0 [max 18.0]
Grading Basis: S-N only
Typically offered: Every Fall, Spring & Summer
Directed laboratory research. prereq: Grad cellular and integrative Phsl major, instr consent
BIOC 4331 - Biochemistry I: Structure, Catalysis, and Metabolism in Biological Systems
Credits: 4.0 [max 4.0]
Course Equivalencies: BioC 3021/BioC 3022/BioC 4331/
Typically offered: Every Fall & Spring
Advanced survey of structure/catalysis, metabolism/bioenergetics. prereq: (BIOL 1009 or 2003 or equiv) AND (Chem 2302 or CHEM 2081/2085 or equiv)
BIOC 4332 - Biochemistry II: Molecular Mechanisms of Signal Transduction and Gene Expression
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
Advanced survey of molecular biology. Mechanisms of gene action/biological regulation. prereq: BioC 4331 or Bioc 3201 or BioC 3022
BIOC 6021 - Biochemistry
Credits: 3.0 [max 3.0]
Course Equivalencies: BioC 3021/BioC 3022/BioC 4331/
Typically offered: Every Fall, Spring & Summer
Fundamentals of biochemistry. Structure/function of proteins, nucleic acids, lipids and carbohydrates. Metabolism, regulation of metabolism. Quantitative treatments of chemical equilibria, enzyme catalysis, and bioenergetics. Chemical basis of genetic information flow. prereq: general biology, organic chemistry, instr consent; intended for MBS students
BIOL 4003 - Genetics
Credits: 3.0 [max 3.0]
Course Equivalencies: Biol 4003/GCD 3022
Typically offered: Every Fall, Spring & Summer
Genetic information, its transmission from parents to offspring, its expression in cells/organisms, and its course in populations. prereq: Biol 2003/2003H or BioC 3021 or BioC 4331 or grad
BIOL 4004 - Cell Biology
Credits: 3.0 [max 3.0]
Course Equivalencies: Biol 4004/GCD 3033/4005W
Typically offered: Every Fall, Spring & Summer
Processes fundamental to cells. Emphasizes eukaryotic cells. Assembly/function of membranes/organelles. Cell division, cell form/movement, intercellular communication, transport, secretion pathways. Cancer cells, differentiated cells. prereq: Completion of Biol 4003 is preferred, Biol2003/2003H or Biol4003 or grad
GCD 5036 - Molecular Cell Biology
Credits: 3.0 [max 3.0]
Typically offered: Every Fall
Analysis of dynamic cellular activities at the molecular level in cell biological fields that are experiencing new research advances not yet reflected in textbooks. Significant emphasis is placed on understanding the experimental basis of our current knowledge of cellular processes through analysis of scientific papers. Project and presentation-based assessments of learning outcomes. prereq: BIOL 4004 or GCD 4005W or grad
PHSL 5096 - Integrative Biology and Physiology Research Advances
Credits: 1.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Fall & Spring
Attend/participate in IBP Fall/Spring seminar series. Seminars given by faculty, invited speakers, students. Exposure to key topics. How to present seminars. prereq: instr consent
PHSL 8777 - Thesis Credits: Master's
Credits: 1.0 -18.0 [max 50.0]
Grading Basis: No Grade
Typically offered: Every Fall, Spring & Summer
(No description) prereq: Max 18 cr per semester or summer; 10 cr total required [Plan A only]
NUTR 8620 - Advances in Nutrition
Credits: 2.0 [max 2.0]
Typically offered: Every Fall & Spring
Recent research or special topics (e.g., obesity, vitamin biochemistry, nutrition education).
PHSL 5197 - Stress Physiology
Credits: 1.0 -3.0 [max 3.0]
Grading Basis: A-F only
Typically offered: Every Spring
Journal club format. Meets weekly to examine foundations of stress, historical progress, development of stress, modern stress physiology. Focus on stress-induced pathology with attention to cardiovascular, metabolic, neuroendocrine disorders. Students participating in the weekly discussion are assessed on discussion participation, completion of weekly writing assignments and quality of the presentation in the class, are eligible for 1 credit. Students completing a midterm (test) and a final project (specific aims page of an NIH RO1 grant) in addition to the criteria described above are eligible for 3 credits. Prerequisite: instructor consent is required. Graduate student standing, master students, and post-doctoral fellows (if they are eligible for credits). Undergraduate students must have taken PHSL 3061 or equivalent, and have previous laboratory research experience.
PHSL 5701 - Physiology Laboratory
Credits: 1.0 -2.0 [max 2.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall & Spring
Experiments in physiology. Emphasizes quantitative aspects, including analysis of organ systems. prereq: instr consent
PHSL 8242 - Professional Skills Development for Biomedical Scientists
Credits: 2.0 [max 1.0]
Grading Basis: A-F only
Typically offered: Periodic Fall, Spring & Summer
Professional skills development, including critical evaluation of the scientific literature, short oral presentations, development of research project specific aims and grant writing. Students will become familiar with strategies/mechanics of writing a grant proposal, NIH study section grant reviews, scientific presentations, dissecting scientific literature, and PubMed/NIHreporter tools. prereq: instr consent
PUBH 6450 - Biostatistics I
Credits: 4.0 [max 4.0]
Grading Basis: A-F only
Typically offered: Every Fall & Spring
This course will cover the fundamental concepts of exploratory data analysis and statistical inference for univariate and bivariate data, including: ? study design and sampling methods, ? descriptive and graphical summaries, ? random variables and their distributions, ? interval estimation, ? hypothesis testing, ? relevant nonparametric methods, ? simple regression/correlation, and ? introduction to multiple regression. There will be a focus on analyzing data using statistical programming software and on communicating the results in short reports. Health science examples from the research literature will be used throughout the course. prereq: [College-level algebra, health sciences grad student] or instr consent
PUBH 6451 - Biostatistics II
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
This course will cover more advanced aspects of statistical analysis methods with a focus on statistical modeling, including: ? two-way ANOVA, ? multiple linear regression, ? logistic regression, ? Poisson regression, ? log binomial and ordinal regression, ? survival analysis methods, including Kaplan-Meier analysis and proportional hazards (Cox) regression, ? power and sample size, and ? survey sampling and analysis. There will be a focus on analyzing data using statistical programming software and on communicating the results in short reports. Health science examples from the research literature will be used throughout the course. prereq: [PubH 6450 with grade of at least B, health sciences grad student] or instr consent
STAT 5021 - Statistical Analysis
Credits: 4.0 [max 4.0]
Typically offered: Every Fall & Spring
Intensive introduction to statistical methods for graduate students needing statistics as a research technique. prereq: college algebra or instr consent; credit will not be granted if credit has been received for STAT 3011