Twin Cities campus

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Twin Cities Campus

Molecular Pharmacology and Therapeutics Minor

Pharmacology
Medical School
Link to a list of faculty for this program.
Contact Information
6-120 Jackson Hall 321 Church St SE Minneapolis, MN 55455 (612) 626-1248
  • Program Type: Graduate minor related to major
  • Requirements for this program are current for Fall 2024
  • Length of program in credits (master's): 9
  • Length of program in credits (doctoral): 12
  • This program does not require summer semesters for timely completion.
Pharmacology is the study of drugs, the mechanisms through which they affect living systems, and the ways in which drugs are acted upon by living systems. A drug is defined as any foreign entity that exerts an effect on a biological system, whereas a therapeutic is a drug that is intentionally administered in order to elicit a favorable outcome. Investigators in the program in Molecular Pharmacology and Therapeutics (MPaT) focus on developing greater insight into the molecular mechanisms that determine biological responses to therapeutic agents, and how underlying biological variation impacts these responses. In addition, MPaT program faculty strive to develop a greater understanding of basic mechanisms of molecular biology, and in particular how these processes are altered in disease states. The ultimate objective of these latter studies is to gain insight that can lead to the development of future novel therapeutic agents. The MPaT graduate minor is designed to prepare students academically and professionally in the field of pharmacological research to make them competent as scientists and competitive as job candidates. Students who have earned their minor from this program occupy a diverse array of high-level positions in the fields of scientific research, drug development and discovery, and medical outreach. The MPaT graduate program consists of 74 faculty trainers, each of whom is equipped to offer students training in highly diverse research areas. Minor students can expect individualized mentorship and training from their advisors. For their part, students are expected to perform at a high level in the lab and classroom, produce publishable scientific data, and to adhere to the standards established by their advisor, the MPaT graduate program, the Department of Pharmacology, and the University.
Program Delivery
  • via classroom (the majority of instruction is face-to-face)
Prerequisites for Admission
Special Application Requirements:
Students interested in the minor are strongly encouraged to confer with their major field advisor and director of graduate studies, and the MPaT director of graduate studies regarding feasibility and requirements.
For an online application or for more information about graduate education admissions, see the General Information section of this website.
Program Requirements
Use of 4xxx courses toward program requirements is permitted under certain conditions with adviser approval.
Minor field courses offered on both the A/F and S/N grading basis must be taken A/F. The minimum cumulative GPA for minor field coursework is 3.00.
Required Coursework (9 to 12 credits)
Master’s students select 9 credits, and doctoral students select 12 credits from the following in consultation with the MPaT director of graduate studies. Other courses can be applied with MPaT director of graduate studies approval.
PHCL 5109 - Introduction to Scientific Communication (1.0-18.0 cr)
PHCL 5110 - Introduction to Pharmacology (3.0 cr)
PHCL 5111 - Pharmacogenomics (3.0 cr)
PHCL 5112 - Foundations of Biomedical Research (1.0-2.0 cr)
PHCL 8026 - Neuro-Immune Interactions (3.0 cr)
PHCL 8208 - Neuropsychopharmacology (3.0 cr)
PHCL 8209 - Substance Abuse at the Bedside (1.0 cr)
PHCL 8211 - Advanced Pharmacology (5.0 cr)
PHCL 8220 - The Ethical Scientist (1.0 cr)
Program Sub-plans
Students are required to complete one of the following sub-plans.
Students may not complete the program with more than one sub-plan.
Masters
Doctoral
 
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PHCL 5109 - Introduction to Scientific Communication
Credits: 1.0 -18.0 [max 18.0]
Typically offered: Every Fall, Spring & Summer
This course is an interactive classroom experience focused on developing student communication skills. The primary emphasis is on student presentations of their research projects. In addition to making verbal presentations, students are expected to provide constructive criticism and feedback to their peers. Students also work on scientific writing skills by preparing a one-page NIH-style Specific Aims page outlining their research project. Prerequisites: student in the Graduate Program in Pharmacology (MS program) or approval from the Director of Graduate Studies Keywords: Pharmacology, Directed, Independent Study, Biomedical, Basic Science, Research, Drug
PHCL 5110 - Introduction to Pharmacology
Credits: 3.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Every Fall
This is a course for first-year students in the Graduate Program in Pharmacology. The course introduces students to the basic principles of pharmacology and focuses on molecular mechanisms of drug action. Topics covered include pharmacokinetics, pharmacodynamics, signal transduction, toxicology pharmacogenomics, and drug discovery. Prerequisites: student in the Graduate Program in Pharmacology or approval from the Course Director(s) Keywords: Introduction, Pharmacology, Molecular, Drug, Pharmacokinetics, Pharmacodynamics, Protein, Pharmacokinetics
PHCL 5111 - Pharmacogenomics
Credits: 3.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Every Spring
Human genetic variation, its implications. Functional genomics, pharmacogenomics, toxicogenomics, proteomics. Interactive, discussion-based course. prereq: Grad student or instr consent Keywords: Pharmacology, Pharmacogenomics, Toxicogenomics, Proteomics, Genetics, Drug
PHCL 5112 - Foundations of Biomedical Research
Credits: 1.0 -2.0 [max 2.0]
Grading Basis: A-F only
Typically offered: Every Fall
This is a course for first-year students in the Graduate Program of Pharmacology. This course will introduce graduate students to the basic operating principles and techniques of a scientific research laboratory, general concepts surrounding experimental design and experimental controls, and familiarity with common laboratory calculations. Discussion of scientific techniques will include recombinant DNA and molecular biology techniques, protein expression and purification, protein assays, biochemical data analysis and fitting methods, transcriptomics and proteomics studies, and cell culture & mouse models of disease. Methods are presented in the context of highlighting general principles in experimental design. Prerequisites: student in the Graduate Program in Pharmacology Keywords: Basic Science, Pharmacology, Personnel, Writing, Presentation, Protein, DNA, Molecule, Microscope, Bioinformatics, Drug
PHCL 8026 - Neuro-Immune Interactions
Credits: 3.0 [max 3.0]
Typically offered: Every Fall
Regulatory systems (neuroendocrine, cytokine, autonomic nervous systems) linking brain/immune systems in brain-immune axis. Functional effects of bidirectional brain-immune regulation. prereq: MICA 8001 or equiv or instr consent
PHCL 8208 - Neuropsychopharmacology
Credits: 3.0 [max 3.0]
Grading Basis: A-F or Aud
Typically offered: Fall Even Year
Relationships between drugs/biochemical, behavioral, neurophysiological consequences. Functional biogenic amine, peptidergic. How manipulations alter neuronal function or behavior. Feedback mechanisms, induction, inhibition. Reinforcement of, tolerance to, or dependence on drugs. prereq: [5212, Psy 5021, Psy 5061] or instr consent
PHCL 8209 - Substance Abuse at the Bedside
Credits: 1.0 [max 1.0]
Grading Basis: S-N only
Typically offered: Every Fall & Spring
Clinical management of addictive diseases. Students discuss how observed clinical interactions can influence a basic science project in which they are involved. prereq: Grad student in any basic-science program
PHCL 8211 - Advanced Pharmacology
Credits: 5.0 [max 5.0]
Grading Basis: A-F only
Typically offered: Every Spring
This hybrid course offers a combination of online and in-class lectures coupled with interactive literature discussion/flipped classroom components. The course has three sections focusing on 1) pharmacology of the autonomic, cardiovascular, and respiratory systems, 2) anti-cancer and anti-microbial therapeutics and 3) pharmacology of the nervous system. Course Instructors will highlight key features of currently utilized therapeutic agents and underscore recent advances in basic and clinical research that underpin emerging or potential approaches to pharmacotherapy. student in the Graduate Program in Pharmacology, or Course Director consent Keywords: Pharmacology, Drug, Therapy, Medical, Biomedical, Clinic
PHCL 8220 - The Ethical Scientist
Credits: 1.0 [max 1.0]
Grading Basis: S-N only
Typically offered: Every Spring
This course focuses on scientific integrity in research and medicine. Topics to be discussed include best practices for experimental design, data collection, and analysis, regulatory requirements for human and animal studies, collaboration and authorship practices, and other social and ethical issues. Prerequisite: student in the Graduate Program in Pharmacology (GPP), or Course Director consent