University of Minnesota, Twin Cities campus

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GCD 4034 - Molecular Genetics and Genomics
Credits: 3.0 [max 3.0]
Typically offered: Every Fall
Molecular genetics and genomics of eukaryotes. Course emphasizes mechanisms of gene regulation and how these are studied. Current strategies used to study the activity and function of genes and genomes, including the role of chromatin, will be covered. Techniques will include gene knockouts/knockdown, genome engineering, genome-wide analysis of RNA and protein expression and function, as well as genome-wide protein binding and chromatin interaction mapping. Technologies covered will include next-generations and third-generation sequencing and CRISPR-based strategies for gene modification and precision gene regulation. Students will analyze and present recent primary papers in molecular genetic and genomics. Prerequisite: BIOL 4003